Challenges in developing a molecular characterization of cancer☆
Abstract
DNA microarrays are widely used to measure gene expression across thousands of genes in parallel. Recently, considerable efforts have been made to utilize this technology to improve our understanding of cancer and to identify novel diagnostic markers and therapeutic targets. Here, we detail some of the challenges in developing a molecular characterization of cancer and in translating these new discoveries towards clinical utility. Semin Oncol 29:280-285. Copyright 2002, Elsevier Science (USA). All rights reserved.
Departments of Pathology and Genetics, Stanford University School of Medicine, Stanford, CA.
☆ Address reprint requests to Jonathan R. Pollack, MD, PhD, Department of Pathology, Stanford University School of Medicine, CCSR Building, Room 3245A, 269 Campus Dr, Stanford, CA 94305-5176.
ABSTRACT