Seminars in Oncology
Volume 29, Issue 6 , Pages 575-584 , December 2002

Complementary and alternative therapies in prostate cancer

References 

  1. Moyad MA. Alternative therapies for advanced prostate cancer. What should I tell my patients?. Urol Clin North Am. 1999;26:413–417
  2. Lippert MC, McClain R, Boyd JC, et al.  Alternative medicine use in patients with localized prostate carcinoma treated with curative intent. Cancer. 1999;86:2642–2648
  3. Kao GD, Devine P. Use of complementary health practices by prostate carcinoma patients undergoing radiation therapy. Cancer. 2000;88:615–619
  4. Nam RK, Fleshner N, Rakovitch E, et al.  Prevalence and patterns of the use of complementary therapies among prostate cancer patientsz: An epidemiological analysis. J Urol. 1999;161:1521–1524
  5. Clinton SK, Giovannucci E. Diet, nutrition, and prostate cancer. Annu Rev Nutr. 1998;18:413–440
  6. Yip I, Heber D, Aronson W. Nutrition and prostate cancer. Urol Clin North Am. 1999;26:403–411
  7. Thomas JA. Diet, micronutrients, and the prostate gland. Nutr Rev. 1999;57:95–103
  8. Barnes S. Effect of genistein on in vitro and in vivo models of cancer. J Nutr. 1995;125:777S–783S (suppl)
  9. Ornish DM, Lee KL, Fair WR, et al.  Dietary trial in prostate cancer: Early experience and implications for clinical trial design. Urology. 2001;57(suppl 1):200–201
  10. Heinonon OP, Albanes D, Virtamo J, et al.  Prostate cancer and supplementation with α-tocopherol and β-carotene: Incidence and mortality in a controlled trial. J Natl Cancer Inst. 1998;90:440–446
  11. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group . The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330:1029–1035
  12. Chan JM, Stampfer MJ, M J , et al.  Supplemental vitamin E intake and prostate cancer risk in a large cohort of men in the United States. Cancer Epidemiol Biomarkers Prev. 1999;8:893–899
  13. Clark LC, Dalkin B, Krongrad A, et al.  Decreased incidence of prostate cancer with selenium supplementation: results of a double-blind cancer prevention trial. Br J Urol. 1998;81:730–734
  14. Yoshizawa K, Willett WC, Morris SJ, et al.  Study of prediagnostic selenium level in toenails and the risk of advanced prostate cancer. J Natl Cancer Inst. 1998;90:1219–1222
  15. Giovannucci E, Ascherio A, Rimm EB, et al.  Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst. 1995;87:1767–1776
  16. Kucuk O, Sarkar FH, Sakr W, et al.  Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy. Cancer Epidemiol Biomarkers Prev. 2001;10:861–868
  17. Hammar M, Frisk J, Grimas O, et al.  Acupuncture treatment of vasomotor symptoms in men with prostatic carcinoma: A pilot study. J Urol. 1999;161:853–856
  18. Hirsh IH. Integrative urology: A spectrum of complementary and alternative therapy. Urology. 2000;56:185–189
  19. Wilt TJ, Ishani A, Stark G, et al.  Saw palmetto extracts for treatment of benign prostatic hyperplasia: A systematic review. JAMA. 1998;280:1604–1609
  20. DiPaola RS, Zhang H, Lambert GH, et al.  Clinical and biologic activity of an estrogenic herbal combination (PC-SPES) in prostate cancer. N Engl J Med. 1998;339:785–791
  21. Moyad MA, Pienta KJ, Montie JE. Use of PC-SPES, a commercially available supplement for prostate cancer, in a patient with hormone-naive disease. Urology. 1999;54:319–323
  22. Hsieh T, Chen SS, Wang X, et al.  Regulation of androgen receptor (AR) and prostate specific antigen (PSA) expression in the androgen-responsive human prostate LNCaP cells by ethanolic extracts of the Chinese herbal preparation, PC-SPES. Biochem Mol Biol Int. 1997;42:535–544
  23. Halicka HD, Ardelt B, Juan G, et al.  Apoptosis and cell cycle effects induced by extracts of the Chinese herbal preparation PC-SPES. Int J Oncol. 1997;11:437–448
  24. Hsieh TC, Ng C, Chang CC, et al.  Induction of apoptosis and down-regulation of bcl-6 in mutu I cells treated with ethanolic extracts of the Chinese herbal supplement PC-SPES. Int J Oncol. 1998;13:1199–1202
  25. de la Taille A, Hayek OR, Buttyan R, et al.  Effects of a phytotherapeutic agent, PC-SPES, on prostate cancer: A preliminary investigation on human cell lines and patients. BJU Int. 1999;84:845–850
  26. de la Taille A, Buttyan R, Hayek O, et al.  Herbal therapy PC-SPES: In vitro effects and evaluation of its efficacy in 69 patients with prostate cancer. J Urol. 2000;164:1229–1234
  27. Tiwari RK, Geliebter J, Garikapaty VP, et al.  Anti-tumor effects of PC-SPES, an herbal formulation in prostate cancer. Int J Oncol. 1999;14:713–719
  28. Kubota T, Hisatake J, Hisatake Y, et al.  PC-SPES: A unique inhibitor of proliferation of prostate cancer cells in vitro and in vivo. Prostate. 2000;42:163–171
  29. Small E, Frohlich M, Bok R, et al.  Prospective trial of the herbal supplement PC-SPES in patients with progressive prostate cancer. J Clin Oncol. 2000;8:3595–3603
  30. Pfeifer BL, Pirani JF, Hamann SR, et al.  PC-SPES, a dietary supplement for the treatment of hormone-refractory prostate cancer. BJU Int. 2000;85:481–485
  31. Oh WK, George DJ, Hackmann K, et al.  Activity of the herbal combination, PC-SPES, in the treatment of patients with androgen-independent prostate cancer. Urology. 2001;57:122–126
  32. Robertson CN, Roberson KM, Padilla GM, et al.  Induction of apoptosis by diethylstilbestrol in hormone-insensitive prostate cancer cells. J Natl Cancer Inst. 1996;88:908–917
  33. Smith DC, Redman BG, Flaherty LE, et al.  A phase II trial of oral diethylstilbesterol as a second-line hormonal agent in advanced prostate cancer. Urology. 1998;52:257–260
  34. Rosenbaum E, Wygoda M, Gips M, et al.  Diethylstilbestrol is an active agent in prostatic cancer patients after failure to complete androgen blockade. Proc Am Soc Clin Oncol. 2000;19:1372; (abstr)

☆ Address reprint requests to William K. Oh, MD, Dana-Farber Cancer Institute, 44 Binney St, Boston, MA 02115.

PII: S0093-7754(02)50320-1

doi: 10.1053/sonc.2002.50007

Seminars in Oncology
Volume 29, Issue 6 , Pages 575-584 , December 2002

Article Tools