Seminars in Oncology
Volume 31, Issue 2 , Pages 137-148, April 2004

Aging biology and cancer

  • Neelima Denduluri

      Affiliations

    • Institute for Advanced Studies in Aging & Geriatric Medicine, Washington, DC, USA
    • ,
  • William B Ershler

      Affiliations

    • Institute for Advanced Studies in Aging & Geriatric Medicine, Washington, DC, USA
    • Corresponding Author InformationAddress reprint requests to William B. Ershler, MD, Institute for Advanced Studies in Aging & Geriatric Medicine, 1700 Wisconsin Ave NW, Washington, DC 20007, USA

Abstract 

Epidemiologic analyses of current registries indicate that the majority of patients in the United States with cancer are 65 years old or older. Basic research in both gerontology and oncology has led to an understanding that these processes (normal aging and the development of cancer) have much in common. In this review we attempt to frame specific aspects of cancer biology in the context of normal aging.

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PII: S0093-7754(03)00663-8

doi:10.1053/j.seminoncol.2003.12.025

Seminars in Oncology
Volume 31, Issue 2 , Pages 137-148, April 2004

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