Seminars in Oncology
Volume 33, Issue 6 , Pages 657-663, December 2006

Adjuvant Hormonal Therapy for Premenopausal Women With Breast Cancer

  • Regina J. Brown
    • ,
  • Nancy E. Davidson

      Affiliations

    • Corresponding Author InformationAddress correspondence to Nancy E. Davidson, MD, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans St, Room 409, Baltimore. MD 21231-1000.

Breast Cancer Program, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

Endocrine therapy is a required element of the management of premenopausal women with early-stage steroid hormone receptor–positive breast cancer. There is uncertainty about how best to implement that therapy using the strategies of tamoxifen and estrogen deprivation as well as how to integrate these approaches with chemotherapy. Other research focuses on identification of improved markers for endocrine response or resistance and on the special side effects of endocrine therapy in young women.

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 Supported in part by National Institutes of Health Grant No. CA88843, and by the Pearl M. Stetler Research Fund Award.

PII: S0093-7754(06)00325-3

doi:10.1053/j.seminoncol.2006.08.014

Seminars in Oncology
Volume 33, Issue 6 , Pages 657-663, December 2006

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