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Seminars in Oncology
Volume 33
, Pages 42-45
, December 2006
Targeted Agents for Adjuvant Therapy of Colon Cancer
References
- Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335–2342
- An international phase II study of cetuximab in combination with oxaliplatin/5-fluorouracil (5-FU)/folinic acid (FA) (FOLFOX-4) in the first-line treatment of patients with metastatic colorectal cancer (CRC) expressing epidermal growth factor receptor (EGFR). Proc Am Soc Clin Oncol. 2004;23:1092s;(abstr 3512)
- Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med. 1990;322:399–401
- . Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet. 1995;345:939–944
- Phase III study of fluorouracil, Leucovorin, and Levamisole in high-risk stage II and III colon cancer/ final report of Intergroup 0089. J Clin Oncol. 2005;23:8671–8678
- Clinical trial to assess the relative efficacy of fluorouracil and leucovorin, fluorouracil and levamisole, and fluorouracil, leucovorin and levamisole, in patients with Dukes’ B and C carcinoma of the colon: Results from National Surgical Adjuvant Breast and Bowel Project protocol C-04. J Clin Oncol. 1999;17:3553–3559
- Controlled trial of fluorouracil and low-dose leucovorin given 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol. 1997;15:246–250
- Semimonthly vs. monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer: Results of a randomized trial. J Clin Oncol. 2003;21:2896–2903
- Capecitabine as adjuvant treatment for stage III colon cancer. N Engl J Med. 2005;352:2696–2704
- Irinotecan plus fluorouracil/leucovorin (IFL) versus fluorouracil/leucovorin alone (FL) in stage III colon cancer (Intergroup trial CALGB C89803). Proc Am Soc Clin Oncol. 2004;23:246;(abstr 3500)
- A phase III randomized trial of LV5FU2+CPT-11 vs. LV5FU2 alone in adjuvant high risk colon cancer (FNCLCC Accord02/FFCD9802). J Clin Oncol. 2005;23;:246s;(abstr 3502)
- Randomized phase III trial comparing infused irinotecan/5-fluorouracil (5-FU)/folinic acid (IF) versus 5-FU/FA (F) in stage III colon cancer patients (pts) (PETACC 3). J Clin Oncol. 2005;23:3s;(abstr LBA8)
- Oxaliplatin, 5-fluorouracil and leucovorin as adjuvant treatment of colon cancer: results of the international randomized MOSAIC trial. N Engl J Med. 2004;350:2343–2351
- Oxaliplatin/5FU/LV in the adjuvant treatment of stage II and stage III colon cancer: Efficacy results with a median follow-up of 4 years. J Clin Oncol. 2005;23:246s;(abstr 3501)
- A phase III trial comparing FULV to FULV + oxaliplatin in stage II or III carcinoma of the colon: Results of NSABP Protocol C-07. J Clin Oncol. 2005;23:16s;(abstr LBA3500)
Dr de Gramont has received honoraria from Roche, Genentech, and Sanofi-Aventis. Dr Tournigand has received honoraria from Roche and Sanofi-Aventis. Dr André has received honoraria from Roche, Merck, and Sanofi-Aventis. Dr Louvet has received honoraria from Roche, Aventis, Amgen, and Sanofi-Aventis.
PII: S0093-7754(06)00383-6
doi: 10.1053/j.seminoncol.2006.10.006
© 2006 Elsevier Inc. All rights reserved.
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Seminars in Oncology
Volume 33
, Pages 42-45
, December 2006
