Seminars in Oncology
Volume 33 , Pages 33-35 , December 2006

Optimum Use of Biologics and Role of Maintenance Therapy in Colon Cancer

  • John Marshall

      Affiliations

    • Corresponding Author InformationAddress reprint requests to John Marshall, MD, Lombardi Cancer Center, Georgetown University Medical Center, 3800 Reservior Road NW, Washington, DC 20057, USA.

References 

  1. Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335–2342
  2. Saltz LB, Lenz H-J, Hochster H, et al. Randomized phase II trial of cetuximab/bevacizumab/irinotecan (CBI) vs cetuximab/bevacizumab (CB) in irinotecan refractory colorectal cancer. Proc Am Soc Clin Oncol. 2005;23:248s;(abstr 3508)
  3. Giantonio BJ, Catalano PJ, Meropol NJ, et al. Results from the Eastern Cooperative Oncology Group (ECOG) study E3200 High-dose bevacizumab improves survival when combined with FOLFOX4 in previously treated advanced colorectal cancer. J Clin Oncol. 2005;23(suppl):1;(abstr 2)
  4. Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med. 2004;351:337–345
  5. Kaiser M, Ellenberg S. Pancreatic cancer: adjuvant combined radiation and chemotherapy following curative resection. Arch Surg. 1985;120:899–903
  6. Kato K, Ichinose Y, Ohta M, et al. A randomized trial of adjuvant chemotherapy with uracil–tegafur for adenocarcinoma of the lung (Japan Lung Cancer Research Group on Postsurgical Adjuvant Chemotherapy). N Engl J Med. 2004;350:1713–1721
  7. Allegra C, Sargent DJ. Adjuvant therapy for colon cancer – The pace quickens. N Engl J Med. 2005;352:2746–2748
  8. Maindrault-Goebel F, Tournigand C, Andre T, et al. Oxaliplatin reintroduction in patients previously treated with leucovorin, fluorouracil and oxaliplatin for metastatic colorectal cancer. Ann Oncol. 2004;15:1210–1214

PII: S0093-7754(06)00385-X

doi: 10.1053/j.seminoncol.2006.10.008

Seminars in Oncology
Volume 33 , Pages 33-35 , December 2006