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Seminars in Oncology
Volume 33
, Pages 46-49
, December 2006
Variation in the Human Genome and the Inherited Basis of Common Disease
References
- Linkage of early-onset familial breast cancer to chromosome 17q21. Science. 1990;250:1684–1689
- Identification and characterization of the familial adenomatous polyposis coli gene. Cell. 1991;66:589–600
- Identification of the breast cancer susceptibility gene BRCA2. Nature. 1995;378:789–792
- . The future of genetic studies of complex human diseases. Science. 1996;273:1516–1517
- A comprehensive review of genetic association studies. Genet Med. 2002;4:45–61
- SinProstate cancer susceptibility genes: Lessons learned and challenges posed. Endocr Relat Cancer. 2003;10:225–259
- Systematic evaluation of genetic variation at the androgen receptor locus and risk of prostate cancer in a multiethnic cohort study. Am J Hum Genet. 2005;76:82–90
- . Variation is the spice of life. Nat Genet. 2001;27:234–236
- . Quality and completeness of SNP databases. Nat Genet. 2003;33:457–458
- . Apolipoprotein E and Alzheimer disease. Proc Natl Acad Sci U S A. 1995;92:4725–4727
- . Resistance to activated protein C caused by the factor VR506Q mutation is a common risk factor for venous thrombosis. Thromb Haemost. 1997;78:483–488
- The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet. 2000;26:76–80
- A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet. 2004;75:330–337
- The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes (Belgian Diabetes Registry). Hum Mol Genet. 1996;5:1075–1080
- Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature. 1996;382:722–725
- Complement factor H polymorphism in age-related macular degeneration. Science. 2005;308:385–389
- Complement factor H variant increases the risk of age-related macular degeneration. Science. 2005;308:419–421
- Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science. 2001;294:1719–1723
- The structure of haplotype blocks in the human genome. Science. 2002;296:2225–2229
- A first-generation linkage disequilibrium map of human chromosome 22. Nature. 2002;418:544–548
- Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet. 2004;74:106–120
- . The International HapMap Project. Nature. 2003;426:789–796
- . Integrating ethics and science in the International HapMap Project. Nat Rev Genet. 2004;5:467–475
- . A haplotype map of the human genome. Nature. 2005;437:1299–1320
- Meta-analysis of genome scans of age-related macular degeneration. Hum Mol Genet. 2005;14:2257–2264
- Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N Engl J Med. 2005;352:2285–2293
- An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays. Cancer Res. 2004;64:3060–3071
- EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science. 2004;304:1497–1500
- Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350:2129–2139
- EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A. 2004;101:13306–13311
- A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. Nat Genet. 2005;37:590–592
PII: S0093-7754(06)00423-4
doi: 10.1053/j.seminoncol.2006.11.001
© 2006 Elsevier Inc. All rights reserved.
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Seminars in Oncology
Volume 33
, Pages 46-49
, December 2006
