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Seminars in Oncology
Volume 34
, Pages S25-S30
, April 2007
Treatment of Advanced Pancreatic Cancer
References
- Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer. Ann Oncol. 1996;7:593–600
- Chemotherapy prolongs survival in inoperable pancreatic carcinoma. Br J Surg. 1994;81:882–885
- Chemotherapy for advanced or metastatic pancreatic cancer: Analysis of 4” randomized trials in 3 decades (1974–2002). Gan To Kagaku Ryoho. 2003;30:CVX1101–CVX1111
- Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreatic cancer: A randomized trial. J Clin Oncol. 1997;15:2403–2413
- Consensus report of the International Society of Gastrointestinal Oncology on therapeutic progress in advanced pancreatic cancer. Cancer. 2006;107:676–685
- Erlotinib plus gemcitabine compared to gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG). [abstr] J Clin Oncol. 2005;23(suppl 1):1
- Gemcitabine versus cisplatin, epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: A randomised controlled multicentre phase III trial. Lancet Oncol. 2005;6:369–376
- Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol. 2002;20:3270–3275
- A randomised, prospective, multicenter, phase III trial of gemcitabine, 5-fluorouracil (5-FU), folinic acid vs. gemcitabine alone in patients with advanced pancreatic cancer. [abstr] J Clin Oncol. 2005;23(suppl 1):4009A
- Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma (A prospective, randomized phase III study of the Gruppo Oncologico dell’italia Meridionale). Cancer. 2002;94:902–910
- Randomized phase III trial of gemcitabine plus cisplatin compared with gemcitabine alone in advanced pancreatic cancer. J Clin Oncol. 2006;24:3946–3952
- Docetaxel plus gemcitabine or docetaxel plus cisplatin in advanced pancreatic carcinoma: Randomized phase II study 40984 of the European Organisation for Research and Treatment of Cancer Gastrointestinal Group. J Clin Oncol. 2005;23:9250–9256
- Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol. 2004;22:3776–3783
- Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer. J Clin Oncol. 2006;24:4441–4447
- A double-blind placebo-controlled, randomized study comparing gemcitabine and marimastat with gemcitabine and placebo as first-line therapy in patients with advanced pancreatic cancer. Br J Cancer. 2002;87:161–167
- Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer. J Clin Oncol. 2004;22:1430–1438
- Gemcitabine: Preclinical pharmacology and mechanisms of action. Semin Oncol. 1996;23(suppl 10):3–15
- Pharmacologically directed design of the dose rate and schedule of 2′,2′-difluorodeoxycytidine (gemcitabine) administration in leukemia. Cancer Res. 1990;50:6823–6826
- Randomized phase II comparison of dose-intense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma. J Clin Oncol. 2003;21:3402–3408
- Phase III trial of gemcitabine (30-minute infusion) versus gemcitabine (fixed-dose-rate infusion (FDR) versus gemcitabine + oxaliplatin (GEMOX) in patients with advanced pancreatic cancer (E6201). [abstr] J Clin Oncol. 2006;24(suppl):LBA4004
- Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: Results of a GERCOR and GISCAD phase III trial. J Clin Oncol. 2005;23:3509–3516
- Phase III randomised comparison of gemcitabine versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer. [abstr PS11] Eur J Cancer. 2005;3(suppl 4):4
- Phase II trial of bevacizumab plus gemcitabine in patients with advanced pancreatic cancer. J Clin Oncol. 2005;23:8033–8040
- Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: A multicenter phase II trial. J Clin Oncol. 2004;22:2610–2616
- Irinotecan plus oxaliplatin and leucovorin-modulated fluorouracil in advanced pancreatic cancer – A Group Tumeurs Digestives of the Fédération Nationale des Centres de Lutte Contre le Cancer Study. J Clin Oncol. 2005;23:1228–1236
- Gemcitabine plus capecitabine versus gemcitabine alone in locally advanced or metastatic pancreatic cancer (A randomized study of the Swiss Group for Clinical Cancer Research (SAKK) and the Central European Cooperative Oncology Group (CECOG)). [abstr] J Clin. 2005;23(suppl):4010
- Growth factors and their receptors in pancreatic cancer. Teratog Carcinog Mutagen. 2001;21:27–44
- Hoffmann-La Roche Media News: US phase III study of Avastin in advanced pancreatic cancer does not meet primary endpoint. Available at: http://www.roche.com/med-cor-2006-06-27 (accessed October 31, 2006)
- Randomized phase II study evaluating oxaliplatin alone, oxaliplatin combined with infusional 5-FU, and infusional 5-FU alone in advanced pancreatic carcinoma patients. Ann Oncol. 2004;15:467–473
- Oxaliplatin combined with 5-FU in second line treatment of advanced pancreatic adenocarcinoma (Results of a phase II trial). Gastroenterol Clin Biol. 2006;30:357–363
PII: S0093-7754(07)00023-1
doi: 10.1053/j.seminoncol.2007.01.006
© 2007 Elsevier Inc. All rights reserved.
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Seminars in Oncology
Volume 34
, Pages S25-S30
, April 2007
