« Previous
Next »
Seminars in Oncology
Volume 34
, Pages S29-S34
, December 2007
Purine Nucleoside Phosphorylase Inhibition as a Novel Therapeutic Approach for B-Cell Lymphoid Malignancies
References
- . Purine nucleoside phosphorylase deficiency. Immunodef Rev. 1991;3:45–81
- . Inhibitors of purine nucleoside phosphorylase. Exp Opin Invest Drugs. 1994;3:1303–1313
- Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)—A novel potent and orally active immunosuppressive agent. Int Immunopharmacol. 2001;1:1199–1210
- . Purine nucleoside phosphorylase inhibitors in T-cell malignancies. Curr Opin Drug Discov Devel. 2004;7:243–247
- Relationship of deoxycytidine kinase and cytoplasmic 5′-nucleotidase to the chemotherapeutic efficacy of 2-chlorodeoxyadenosine. Blood. 1993;81:597–601
- Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells. Blood. 2006;108:2392–2398
- Intravenous forodesine (BCX-1777), a novel purine nucleoside phosphorylase (PNP) inhibitor, demonstrates clinical activity in phase I/II studies in patients with B-cell acute lymphoblastic leukemia. Blood. 2004;104(suppl 1):750a;(abstr 2743)
- Phase II study of forodesine, a PNP inhibitor, in patients with relapsed or refractory B-lineage acute lymphoblastic leukemia. 2006;Poster presented at the American Society of Hematology 48th Annual Meeting, Orlando, FL, December
PII: S0093-7754(07)00223-0
doi: 10.1053/j.seminoncol.2007.11.004
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
Seminars in Oncology
Volume 34
, Pages S29-S34
, December 2007
