Seminars in Oncology
Volume 35, Issue 2 , Pages 100-107, April 2008

Current Neurosurgical Management of Brain Metastases

  • David W. Andrews

      Affiliations

    • Corresponding Author InformationAddress correspondence to David W. Andrews, MD, 909 Walnut St, 2nd Floor, Thomson Jefferson University, Jefferson Medical College, Philadelphia, PA 19107.

Department of Neurosurgery, Thomson Jefferson University, Jefferson Medical College, Philadelphia, PA.

Brain metastases occur in a third of patients diagnosed with cancer; without any intervention, the prognosis is quite poor with a median survival of 1 month. Because of the constraints of the blood-brain barrier, chemotherapy is not effective and treatment options include surgery, whole brain radiation, or stereotactic radiation. This chapter is devoted to a review of the current management options for treatment of brain metastases.

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PII: S0093-7754(07)00272-2

doi:10.1053/j.seminoncol.2007.12.003

Seminars in Oncology
Volume 35, Issue 2 , Pages 100-107, April 2008