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Seminars in Oncology
Volume 36
, Pages S17-S24
, August 2009
Understanding the Origins of Gliomas and Developing Novel Therapies: Cerebrospinal Fluid and Subventricular Zone Interplay
References
- . Factors influencing survival in high-grade gliomas. Semin Oncol. 2003;30(Suppl 19):10–14
- Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J Natl Cancer Inst. 1993;85:704–710
- . Brain tumors. N Engl J Med. 2001;344:114–123
- Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial. J Clin Oncol. 2006;24:2563–2569
- Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987–996
- . Assumptions in the radiotherapy of glioblastoma. Neurology. 1980;30:907–911
- . Patterns of failure following treatment for glioblastoma multiforme and anaplastic astrocytoma. Int J Radiat Oncol Biol Phys. 1989;16:1405–1409
- Frequency and prognostic significance of a positive cerebrospinal fluid (CSF) cytology in patients with gliomas [abstract]. Neurology. 1997;48:A35
- Relationship of glioblastoma multiforme to neural stem cell regions predicts invasive and multifocal tumor phenotype. Neurooncology. 2007;9:424–429
- . The subependymal cell plate (matrix) and its relationship to brain tumors of the ependymal type. J Neuropathol Exp Neurol. 1944;3:1–35
- . Transplacental induction of malignant tumors of the nervous system (I. Ethyl-nitroso-urea (ENU) in BD IX rats). Z Krebsforsch. 1968;71:320–360
- . The importance of implantation site in cerebral carcinogenesis in rats. Cancer Res. 1969;29:1927–1931
- . Long-distance neuronal migration in the adult mammalian brain. Science. 1994;264:1145–1148
- . Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron. 1993;11:173–189
- . Young neurons from the adult subependymal zone proliferate and migrate along an astrocyte, extracellular matrix-rich pathway. Glia. 1996;17:1–14
- In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. Proc Natl Acad Sci U S A. 2000;97:14686–14691
- Neural stem cells and cholinergic neurons: regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor. Proc Natl Acad Sci U S A. 2003;100:7325–7330
- . In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J Neurosci. 1996;16:2649–2658
- . Applying the principles of stem-cell biology to cancer. Nat Rev Cancer. 2003;3:895–902
- . Stem cells, cancer, and cancer stem cells. Nature. 2001;414:105–111
- . Adult neurogenesis and neural stem cells of the central nervous system in mammals. J Neurosci Res. 2002;69:745–749
- . Mechanisms of disease: the role of stem cells in the biology and treatment of gliomas. Nat Clin Pract Oncol. 2008;5:393–404
- . A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev. 1998;12:3675–3685
- . Up-regulation of neuropoiesis generating glial progenitors that infiltrate rat intracranial glioma. J Neurooncol. 2005;71:245–255
- Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival. J Neurosci. 2005;25:2637–2646
- Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea. Am J Pathol. 2006;168:1676–1685
- . The stem-cell niche as an entity of action. Nature. 2006;441:1075–1079
- Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science. 2004;304:1338–1340
- A perivascular niche for brain tumor stem cells. Cancer Cell. 2007;11:69–82
- . Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors. Cancer Res. 2007;67:3560–3564
- . Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci U S A. 2004;101:781–786
- Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003;63:5821–5828
- Identification of human brain tumour initiating cells. Nature. 2004;432:396–401
- Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene. 2004;23:9392–9400
- Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure. J Neurosurg. 2005;102:98–108
- PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling. Neuron. 2006;51:187–199
- . Tumorigenesis of chemotherapeutic drug-resistant cancer stem-like cells in brain glioma. Stem Cells Dev. 2007;16:837–847
- Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer. 2006;5:67–78
- . Mechanisms of disease: cancer stem cells-targeting the evil twin. Nat Clin Pract Oncol. 2008;5:337–347
- CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain. Proc Natl Acad Sci U S A. 2008;105:1026–1031
- CD133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells. Cancer Res. 2007;67:5727–5736
- Genetic aberrations defined by comparative genomic hybridization distinguish long-term from typical survivors of glioblastoma. Cancer Res. 2002;62:6205–6210
- Genetic analysis of glioblastoma multiforme provides evidence for subgroups within the grade. Genes Chromosomes Cancer. 1998;21:195–206
- Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res. 2005;65:1678–1686
- Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006;9:157–173
- Contribution of Notch signaling activation to human glioblastoma multiforme. J Neurosurg. 2007;106:417–427
- . Malignant gliomas in adults. N Engl J Med. 2008;359:492–507
- . On the neuronal/neuroblastic nature of medulloblastomas: a tribute to Pio del Rio Hortega and Moises Polak. Acta Neuropathol. 2003;105:1–13
- Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med. 2005;352:978–986
- . Current treatment approaches to early childhood medulloblastoma. Expert Rev Neurother. 2006;6:1211–1221
- . The role of HD chemotherapy (CT) in the treatment of therapy-resistant CNS PNETs (HIT-REZ-97 results). Hematol Rep. 2006;2:1–15
- . Cancer stem cells in radiation resistance. Cancer Res. 2007;67:8980–8984
- . CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo. J Biol. 2006;5:22–36
- . Regeneration of a germinal layer in the adult mammalian brain. Proc Natl Acad Sci U S A. 1999;96:11619–11624
- Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756–760
- . Chemoradiotherapy for primary CNS lymphoma: an intent-to-treat analysis with complete follow-up. Neurology. 2005;64:69–74
- . Methotrexate: distribution in cerebrospinal fluid after intravenous, ventricular and lumbar injections. N Engl J Med. 1975;293:161–166
- . Optimal two-stage designs for phase II clinical trials. Control Clin Trials. 1989;10:1–10
STATEMENT OF CONFLICT OF INTEREST: M.G. has received honoraria and research support from Enzon Pharmaceuticals. The other authors have nothing to disclose.
PII: S0093-7754(09)00093-1
doi: 10.1053/j.seminoncol.2009.05.003
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Seminars in Oncology
Volume 36
, Pages S17-S24
, August 2009
