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Volume 36, Issue 5, Pages 419-431 (October 2009)


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Melanoma in Pediatric, Adolescent, and Young Adult Patients

John M. KirkwoodaCorresponding Author Informationemail address, Drazen M. Jukicb, Bruce J. Averbookc, Leonard S. Senderd

The family practitioner, pediatrician, and dermatologist all have potential roles in the primary prevention, diagnosis, and treatment of localized thin melanomas. Surgical and medical oncologists are often involved when controversy arises over the nature of the skin lesion or whether sentinel lymph node (SLN) biopsies and adjuvant therapy are to be contemplated. This overview of melanoma will deal with the primary and nodal pathology, surgery, and medical therapy of melanoma in pediatric, adolescent, and young adult patients—and will raise areas of controversy that are only recently being addressed in databases of cases from this age group.

a Departments of Medicine and Dermatology, University of Pittsburgh School of Medicine, and Melanoma and Skin Cancer Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA

b Departments of Dermatology and Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA

c Departments of Surgery and General Medical Sciences (Oncology), MetroHealth Medical Center/Case Western Reserve University, Cleveland, OH

d Department of Medicine, University of California, Irvine, and CHOC Children's Hospital, Orange, CA

Corresponding Author InformationAddress correspondence to John M. Kirkwood, MD, Hillman Cancer Research Pavillion, Melanoma Program, 5117 Centre Ave, Ste L132c, Pittsburgh, PA 15213

 Funded by NIH SPORE in Skin Cancer Grant No. P50 CA121973-02, and supported by the Clinical and Translational Science Institute and the Grant Channell Foundation.

PII: S0093-7754(09)00136-5

doi:10.1053/j.seminoncol.2009.07.001


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