Melanoma in Pediatric, Adolescent, and Young Adult Patients
The family practitioner, pediatrician, and dermatologist all have potential roles in the primary prevention, diagnosis, and treatment of localized thin melanomas. Surgical and medical oncologists are often involved when controversy arises over the nature of the skin lesion or whether sentinel lymph node (SLN) biopsies and adjuvant therapy are to be contemplated. This overview of melanoma will deal with the primary and nodal pathology, surgery, and medical therapy of melanoma in pediatric, adolescent, and young adult patients—and will raise areas of controversy that are only recently being addressed in databases of cases from this age group.
aDepartments of Medicine and Dermatology, University of Pittsburgh School of Medicine, and Melanoma and Skin Cancer Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA
bDepartments of Dermatology and Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA
cDepartments of Surgery and General Medical Sciences (Oncology), MetroHealth Medical Center/Case Western Reserve University, Cleveland, OH
dDepartment of Medicine, University of California, Irvine, and CHOC Children's Hospital, Orange, CA
Address correspondence to John M. Kirkwood, MD, Hillman Cancer Research Pavillion, Melanoma Program, 5117 Centre Ave, Ste L132c, Pittsburgh, PA 15213
Funded by NIH SPORE in Skin Cancer Grant No. P50 CA121973-02, and supported by the Clinical and Translational Science Institute and the Grant Channell Foundation.