Seminars in Oncology

Current Clinical Practice

At times we encounter clinical problems for which there are no directly applicable evidence-based solutions, but we are compelled by circumstances to act. When doing so we rely on related evidence, general principles of best medical practice, and our experience. Each "Current Clinical Practice" feature article in Seminars in Oncology describes such a challenging presentation and offers treatment approaches from selected specialists. We invite readers' comments and questions, which, with your approval, will be published in subsequent issues of the Journal. It is hoped that sharing our views and experiences will better inform our management decisions when we next encounter similar challenging patients. Please send your comments on the articles, your challenging cases, and your treatment successes to me at Gloria.Morris@hemonc1.com. I look forward to a lively discussion.

Gloria J. Morris, MD, PhD, Current Clinical Practice Feature Editor

Article Title	Author(s)	Type	Pages
A Wealth of New Options: A Case Presentation of the Management of Castration-Recurrent Prostate Cancer February 2012 (Vol. 39 \| No. 1 \| Pages 1-8) Full Text PDF (304 KB)	Douglas F. Beach, Robert A. Somer, Jean Hoffman-Censits, Jianqing Lin, Yu-Ning Wong, Elizabeth Plimeck, Gary Hudes, David Vaughn, Guy T. Bernstein, Gloria J. Morris et al.	Full-length article	1-8
Early-Stage Hodgkin Disease in a 24-Year-Old Woman December 2011 (Vol. 38 \| No. 6 \| Pages 705-713) Full Text PDF (1732 KB)	Christopher Peters, Eli Glatstein, Julie Vose, Lisa C. Thomas, Gloria J. Morris et al.	Full-length article	705-713
Low-Grade Follicular Lymphoma of the Small Intestine: A Challenge for Management December 2011 (Vol. 38 \| No. 6 \| Pages 714-720) Full Text PDF (1645 KB)	Nabila Bennani-Baiti, Hamed A. Daw, Claudiu Cotta, Peter Martin, Kelly W. Mitchell, Richard F. Ambinder, Roger Macklis, Raphael Pollock, Timothy Spiro et al.	Full-length article	714-720
BRCA1 and BRCA2 Variants of Uncertain Significance. Part Two: Medical Management October 2011 (Vol. 38 \| No. 5 \| Pages 605-611) Full Text PDF (237 KB)	Susan Miller-Samuel, Anne Rosenberg, Adam Berger, Leonard Gomella, David Loren, Gloria J. Morris et al.	Full-length article	605-611
Variants of Uncertain Significance in Breast Cancer–Related Genes: Real-World Implications for a Clinical Conundrum. Part One: Clinical Genetics Recommendations August 2011 (Vol. 38 \| No. 4 \| Pages 469-480) Full Text PDF (437 KB)	Susan Miller-Samuel, Deborah J. MacDonald, Jeffrey N. Weitzel, Ferdy Santiago, Martin A. Martino, Tara Namey, AnnMarie Augustyn, Rebecca Mueller, Andrea Forman, Angela R. Bradbury, Gloria J. Morris et al.	Full-length article	469-480
Monoclonal Gammopathy of Undetermined Significance Versus Smoldering Myeloma: Is Active Surveillance Enough? June 2011 (Vol. 38 \| No. 3 \| Pages 327-334) Full Text PDF (2738 KB)	W. Edward Jordan, Robert Emmons, Daniel Vogl, Gloria J. Morris	Full-length article	327-334
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma With Pancytopenia and Chylothorax April 2011 (Vol. 38 \| No. 2 \| Pages 165-170) Full Text PDF (949 KB)	Lisa C. Thomas, Matthew J. Maida, Ubaldo Martinez-Outschoorn, Joanne Filicko-O'Hara, Gloria J. Morris et al.	Full-length article	165-170
Testicular Lymphoma December 2010 (Vol. 37 \| No. 6 \| Pages 549-554) Full Text PDF (1224 KB)	Lisa C. Thomas, Christian Adonizio, Joanne Filicko-O'Hara, Ali R. Golshayan, Luciano J. Costa, Gloria J. Morris et al.	Full-length article	549-554
Readers' Responses to “Cancer of Unknown Primary Site: Advances in Diagnostics” December 2010 (Vol. 37 \| No. 6 \| Page 555) Full Text PDF (124 KB)	Robert Emmons, Gloria J. Morris	Full-length article	555-555
Recurrent Early-Stage Triple-Negative Breast Cancer October 2010 (Vol. 37 \| No. 5 \| Pages 419-428) Full Text PDF (321 KB)	Christian S. Adonizio, Genorosa Grana, Kanu Sharan, Lewis Rose, Allison Zibelli, Susan Miller-Samuel, Gloria J. Morris et al.	Full-length article	419-428
Surgically Unresectable Regional Melanoma Metastases in a Patient With Renal Failure and Peripheral Vascular Disease: Are There Safe and Potentially Effective Treatments? August 2010 (Vol. 37 \| No. 4 \| Pages 303-313) Full Text PDF (3191 KB)	Kendra Feeney, Henry C. Maguire, Edward F. McClay, Takami Sato, Vernon K. Sondak, Mary Toporcer, Jonathan S. Zager et al.	Full-length article	303-313
Mucinous Adenocarcinoma of the Ovary August 2010 (Vol. 37 \| No. 4 \| Pages 314-320) Full Text PDF (886 KB)	Abdalla Sholi, Martin M. Martino, Megan Pirigyi, Norman G. Rosenblum, Maurie Markman, Candace S. Peterson, Angela R. Bradbury, Gloria J. Morris et al.	Full-length article	314-320
Gastric Mucosa-Associated Lymphoid Tissue Lymphoma June 2010 (Vol. 37 \| No. 3 \| Pages 183-187) Full Text PDF (1936 KB)	Gloria J. Morris, Efrat Dotan, Mitchell R. Smith, Frederick B. Hagemeister, Harmar D. Brereton et al.	Full-length article	183-187
The Role of Anti-Tumor Necrosis Factor Receptor Agents in Cancer Survivors Revisited June 2010 (Vol. 37 \| No. 3 \| Pages 188-189) Full Text PDF (127 KB)	Edward F. McClay	Full-length article	188-189
Cancer of Unknown Primary Site April 2010 (Vol. 37 \| No. 2 \| Pages 71-79) Full Text PDF (2351 KB)	Gloria J. Morris, Frank A. Greco, John D. Hainsworth, Paul F. Engstrom, Salvatore Scialla, W. Edward Jordan, Lisa C. Thomas et al.	Full-length article	71-79
Readers' Responses to “Breast Cancer With Positive Sentinel Lymph Node: Now What?” April 2010 (Vol. 37 \| No. 2 \| Pages 80-81) Full Text PDF (117 KB)	Harmar D. Brereton, Richard G. Emanuelson, Gloria J. Morris	Full-length article	80-81
Residual Disease After Neoadjuvant Chemotherapy for Breast Cancer February 2010 (Vol. 37 \| No. 1 \| Pages 1-10) Full Text PDF (2992 KB)	Gloria J. Morris, Patricia A. Robinson, Shelly Lo, Thomas A. Samuel, Asad A. Sheikh, W. Edward Jordan, Lisa C. Thomas, Krystyna Kiel, Christopher A. Peters et al.	Full-length article	1-10
The Role of Anti–Tumor Necrosis Factor Receptor Agents in Cancer Survivors: Does the Risk Justify the Benefit? February 2010 (Vol. 37 \| No. 1 \| Pages 11-19) Full Text PDF (1918 KB)	Paul Chapman, Lee Cranmer, W.G. Dixon, K.L. Hyrich, John R. Patterson, D.P.M. Symmons, Mary Toporcer, Michael J. Mastrangelo et al.	Full-length article	11-19
Squamous Cell Carcinoma of the Esophagus: Treat With How Many Modalities? December 2009 (Vol. 36 \| No. 6 \| Pages 493-497) Full Text PDF (280 KB)	Suzan Cheng, Mark Iannettoni, Matthew Koshy, Mohan Suntharalingam, Susan Urba et al.	Full-length article	493-497
Completely Regressed Cutaneous Melanocytic Lesion Revisited December 2009 (Vol. 36 \| No. 6 \| Pages 498-503) Full Text PDF (1819 KB)	Timothy W. McCardle, Jane L. Messina, Vernon K. Sondak	Full-length article	498-503