Seminars in Oncology

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Seminars in Oncology

Volume 35, Supplement 3 (June 2008)

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A New Microtubule Targeting Agent (MTA): Vinflunine. From Discovery to Patient Treatment

Edited by Susan Band Horowitz MD

Pierre Fabre

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page IFC
Full-Text PDF (43 KB)

Introduction
Susan Band Horwitz
pages S1-S2
Full Text | Full-Text PDF (44 KB)

Vinflunine: Discovery and Synthesis of a Novel Microtubule Inhibitor
Jacques Fahy, Paul Hellier, Fabienne Breillout, Christian Bailly
pages S3-S5
Full Text | Full-Text PDF (301 KB)

Exploring the Mechanisms of Action of the Novel Microtubule Inhibitor Vinflunine
Mary Ann Jordan, Susan Band Horwitz, Sharon Lobert, John J. Correia
pages S6-S12
Abstract | Full Text | Full-Text PDF (474 KB)

Antitumor Activity of Vinflunine: Effector Pathways and Potential for Synergies
Diane Braguer, Jean-Marc Barret, Hayley McDaid, Anna Kruczynski
pages S13-S21
Abstract | Full Text | Full-Text PDF (1909 KB)

Potential Mechanisms of Resistance to Microtubule Inhibitors
Maria Kavallaris, Jean-Philippe Annereau, Jean-Marc Barret
pages S22-S27
Abstract | Full Text | Full-Text PDF (255 KB)

Pharmacokinetics, Metabolites, and Preclinical Safety of Vinflunine
Sharon Lobert, Christian Puozzo
pages S28-S33
Abstract | Full Text | Full-Text PDF (419 KB)

Clinical Activity of Vinflunine in Transitional Cell Carcinoma of the Urothelium and Other Solid Tumors
Joaquim Bellmunt, Francois-Michel Delgado, Claude George
pages S34-S43
Abstract | Full Text | Full-Text PDF (115 KB)

Frontmatter

Table of Contents
page A1
Full-Text PDF (32 KB)

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